3- Postdoctoral Research Fellows in Proteomics at the University of Helsinki, Finland

The University of Helsinki is inviting applications for three Postdoctoral Research Fellow positions in proteomics, focusing on neurodevelopment, acute myeloid leukemia (AML), and drug toxicity and efficacy.

The positions are hosted by the Varjosalo group and the newly established Järvinen group at the Institute of Biotechnology (HiLIFE). The research uses advanced mass spectrometry-based proteomics to investigate how proteins, protein interactions, and post-translational modifications influence disease mechanisms and drug responses.

Position Overview

Detail        Information
Positions        3 Postdoctoral Research Fellows
Institution        University of Helsinki
Institute        Institute of Biotechnology, HiLIFE
Location        Helsinki, Finland
Research areas        Proteomics, neurodevelopment, cancer, drug toxicity
Salary        Approximately €3,900–€4,376 gross/month
Contract        2–3 years
Trial period        6  months
Expected start        1 October 2026 or as agreed
Application deadline        30 September 2026
Language        English

Applications are reviewed on a rolling basis, and the positions may be filled before the deadline if suitable candidates are identified.


1. Postdoctoral Fellow – Neurodevelopmental Proteomics

The first position focuses on understanding the molecular circuitry of human neurodevelopment using advanced cellular models and patient-derived material.

The project combines 2D and 3D cell models, differentiation systems, organoids and assembloids with quantitative proteomics approaches. The objective is to understand how genetic variants affect protein networks involved in neurodevelopment.

Research activities

The successful candidate will work with:

  • Human neurodevelopmental models

  • Stem-cell-derived systems

  • Organoids and assembloids

  • Patient-derived clinical material

  • Interaction proteomics

  • Expression proteomics

  • Quantitative molecular data

  • Protein networks associated with genetic variants

The project involves collaboration with neurobiology researchers from the Neuroscience Center and Karolinska Institute.

Ideal background

Applicants should preferably have experience in:

  • Stem cell biology

  • Neurobiology

  • Developmental biology

  • Quantitative biological research

Mass spectrometry experience is advantageous but not mandatory. The research group will provide training for candidates without prior mass spectrometry experience.


2. Postdoctoral Fellow – Clinical Proteomics of Acute Myeloid Leukemia

The second position focuses on acute myeloid leukemia (AML) and uses clinical proteomics to investigate disease progression, relapse and drug resistance.

The researcher will work with patient-derived AML specimens to characterize their proteome and interactome.

Research focus

The project aims to understand:

  • How AML is organized at the protein level

  • Molecular mechanisms underlying disease relapse

  • Development of drug resistance

  • Protein interactions associated with disease progression

  • Potential mechanisms relevant to patient treatment

The project has a strong translational component because it is conducted in collaboration with clinical hematologists at the University Hospital.

Ideal background

Applicants should have:

  • Hands-on experience handling clinical patient material

  • Experience preparing biological samples for molecular analysis

  • An understanding of disease biology

  • Strong interest in quantitative data analysis

  • Ability to connect molecular findings with clinical questions

This position may be particularly attractive to researchers with backgrounds in cancer biology, molecular biology, clinical research, proteomics or biomedical sciences.


3. Postdoctoral Fellow – Chemoproteomics of Drug Toxicity and Efficacy

The third position is based in the newly established research group of Dr. Erkka Järvinen and focuses on chemoproteomics, drug target engagement, drug efficacy and toxicity.

The researcher will investigate how drugs interact with their targets and how these interactions influence cellular phenotypes.

Research focus

The work includes:

  • Chemoproteomic approaches

  • Target engagement

  • Target selectivity

  • Activity-based profiling

  • Global proteomics

  • Phosphoproteomics

  • Phenotype deconvolution

  • Machine-learning-based data analysis

  • Drug-induced liver toxicity

  • Drug efficacy

The project provides an opportunity to contribute to the development of a new research direction within the Järvinen group.

Suitable backgrounds

Candidates may come from areas such as:

  • Chemical biology

  • Biosciences

  • Medicinal chemistry

  • Proteomics

  • Molecular biology

  • Data-rich biological sciences

A strong interest in small molecules and drug mechanisms will be valuable.

The project also connects closely with the group's AML research.


General Eligibility Requirements

The University of Helsinki expects candidates for all three positions to have:

  • A doctoral degree in a relevant field, either completed or close to completion at the time of appointment.

  • A publication record appropriate to their career stage.

  • Ability to independently plan and conduct research.

  • Willingness to contribute to the research group's activities.

  • Interest in research fundraising.

  • Excellent written and spoken English.

Finnish language skills are not required.

The selected candidates are expected to reside in Finland while employed by the University of Helsinki.


Salary and Benefits

The salary follows the Finnish university salary system, at requirement level 5, with an additional personal performance component.

Salary

Approximately €3,900–€4,376 gross per month.

The appointment is for 2–3 years, with a six-month trial period.

Additional benefits

The University of Helsinki offers several benefits, including:

  • Occupational healthcare

  • Subsidized lunch

  • Holiday bonus

  • Parental leave system

  • International working environment

  • Relocation support

  • Assistance with residence permits

  • Support for finding schools and daycare

  • International Staff Services

Helsinki is an international city where English is widely used, including within the university community.


Why Choose the University of Helsinki?

The research is conducted within HiLIFE – Helsinki Institute of Life Science, an interdisciplinary research environment supporting high-quality life-science research across the University of Helsinki.

The research groups have direct access to the Helsinki Proteomics Center (HPC), Finland's national proteomics infrastructure.

Researchers can therefore work with extensive state-of-the-art instrumentation across the University's Viikki and Meilahti campuses.

The combination of:

  • Advanced mass spectrometry

  • Clinical collaborations

  • Quantitative proteomics

  • Molecular biology

  • Computational analysis

  • Drug discovery

  • Disease research

makes these positions particularly relevant for researchers interested in translational and technology-driven life-science research.


Application Process

Applications must be submitted through the University of Helsinki recruitment system.

Applications sent by email will not be considered.

Required documents

Applicants should prepare:

  1. CV
  2. Publication list
  3. One-page motivation letter
  4. The motivation letter should clearly state which position—or positions—you are applying for.
  5. Contact details of 2–3 referees

Candidates may apply for more than one position, but should clearly indicate their preference in the motivation letter.

Application deadline

30 September 2026

Because applications are reviewed on a rolling basis, candidates should not necessarily wait until the deadline to apply.

APPLY HERE: University of Helsinki recruitment system


Which Position Should You Apply For?

Your background should determine which project you target.

Your backgroundBest-fit position
Stem cell biologyNeurodevelopmental Proteomics
NeurobiologyNeurodevelopmental Proteomics
Developmental biologyNeurodevelopmental Proteomics
Clinical molecular biologyAML Clinical Proteomics
Cancer biologyAML Clinical Proteomics
Hematology-related researchAML Clinical Proteomics
Clinical sample processingAML Clinical Proteomics
ProteomicsAny of the three
Mass spectrometryAny of the three
Chemical biologyChemoproteomics
Medicinal chemistryChemoproteomics
Drug discoveryChemoproteomics
PhosphoproteomicsChemoproteomics
Bioinformatics/data-rich biologyParticularly Chemoproteomics

Importantly, mass spectrometry experience is not mandatory for the neurodevelopmental position, making that position potentially suitable for candidates coming from stem-cell, developmental or neurobiology backgrounds.


About HiLIFE

The Helsinki Institute of Life Science (HiLIFE) was established in 2017 and supports interdisciplinary life-science research across the University of Helsinki.

HiLIFE brings together researchers, infrastructures and partnerships addressing major challenges in areas including:

  • Health
  • Food
  • Environment
  • Molecular biology
  • Biotechnology
  • Biomedical research

The institute also coordinates life-science research infrastructures and provides interdisciplinary research training.


Frequently Asked Questions

1. How many postdoctoral positions are available?

There are three Postdoctoral Research Fellow positions at the University of Helsinki.

They cover:

  1. Neurodevelopmental proteomics
  2. Clinical proteomics of acute myeloid leukemia
  3. Chemoproteomics of drug toxicity and efficacy

2. What is the salary?

The gross monthly salary is approximately €3,900–€4,376, depending on the Finnish university salary system and personal performance component.

3. How long is the contract?

The appointment is for 2–3 years, with a six-month trial period.

4. When does the position start?

The expected starting date is 1 October 2026 or as agreed.

5. Do I need Finnish language skills?

No. Finnish is not required, and excellent English communication skills are expected.

6. Can I apply for more than one position?

Yes. Applicants may apply to more than one research area. If doing so, clearly state your preferred position or positions in the motivation letter.

7. Is mass spectrometry experience mandatory?

Not for all positions. For the neurodevelopmental proteomics position, prior mass spectrometry experience is welcome but not required, as training will be provided.

8. What documents are required?

You need:

  • CV
  • Publication list
  • One-page motivation letter
  • Contact details of 2–3 referees

9. Can I apply by email?

No. Applications must be submitted through the University of Helsinki recruitment system. Email applications will not be considered.

10. What is the application deadline?

The deadline is 30 September 2026. However, applications are reviewed on a rolling basis, and positions may be filled before the deadline.

11. Do I need to live in Finland?

Selected applicants are expected to reside in Finland while employed by the University of Helsinki.

12. Is relocation support available?

Yes. International Staff Services can assist international researchers with relocation, residence permits, schools and daycare arrangements.


Final Takeaway

These three University of Helsinki postdoctoral positions provide opportunities to work at the intersection of proteomics, molecular biology, clinical research and drug response.

The strongest applicants will have a relevant PhD, a good publication record and the ability to work independently. However, the positions are deliberately multidisciplinary: candidates do not necessarily need to come from a traditional proteomics background.

If your expertise is in neurodevelopment, stem cells, cancer biology, clinical research, chemical biology, medicinal chemistry, mass spectrometry or quantitative bioscience, at least one of these projects could be a strong match.

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