Bayer Postdoc Position in Proteomics, Drug Metabolism & Pharmacokinetics (DMPK) – Germany (2026)

Bayer is inviting applications for a highly interdisciplinary Postdoc DMPK (in vitro ADME & IC) – Proteomics position in Germany. This opportunity is designed for early-career researchers interested in:

• proteomics,
• mass spectrometry,
• pharmacokinetics,
• drug metabolism,
• toxicology,
• systems biology,
• and translational pharmaceutical research.

The position is based within Bayer’s Pharmaceuticals Division in Wuppertal-Aprath, North Rhine-Westphalia, Germany.

This role offers hands-on industrial postdoctoral research experience at one of the world’s leading life science and pharmaceutical companies.

About Bayer

Bayer is a global leader in:

• healthcare,
• pharmaceuticals,
• biotechnology,
• crop science,
• and life sciences innovation.

The company’s mission “Health for All, Hunger for None” focuses on:

• improving global health,
• supporting sustainable agriculture,
• and addressing climate-related challenges.

Bayer combines:

• scientific innovation,
• advanced pharmaceutical development,
• and interdisciplinary collaboration

to develop next-generation healthcare solutions.

Position Overview

Feature	Details
Position	Postdoc DMPK (in vitro ADME & IC) – Proteomics
Company	Bayer
Division	Pharmaceuticals
Location	Wuppertal-Aprath, Germany
Contract Duration	Initial 12 Months
Start Date	As soon as possible
Research Area	Proteomics & Drug Metabolism
Reference Code	867667

Research Focus

The postdoctoral researcher will work at the intersection of:

• proteomics,
• pharmacokinetics (PK),
• toxicology,
• and drug metabolism.

The role focuses on understanding:

• on-target and off-target drug effects,
• protein degradation pathways,
• target occupancy,
• and PK/PD relationships for novel drug modalities.

This research is especially relevant for:

• covalent binders,
• targeted protein degraders,
• and next-generation therapeutics.

Main Responsibilities

The selected researcher will contribute to multiple advanced proteomics and pharmaceutical research activities.

1. Proteomics-Based Drug Research

The researcher will:

• use advanced proteomics methods,
• investigate drug-target interactions,
• and study molecular mechanisms involved in therapeutic development.

Key focus areas include target occupancy, targeted protein degradation, and molecular characterization of drug candidates.

2. Method Development and Optimization

The role includes:

• developing new proteomics workflows,
• optimizing existing analytical methods,
• and improving experimental pipelines for translational pharmaceutical research.

Researchers will contribute to disease mechanism studies, PK/PD relationships, and toxicological evaluations.

3. Multi-Omics Integration

The postdoc will implement multi-omics approaches within:

• preclinical drug development,
• toxicology studies,
• and pharmacological safety assessments.

This involves integrating proteomics, bioinformatics, and systems biology data.

Required Qualifications

Applicants should possess:

• PhD in biology, biochemistry, analytical chemistry, life sciences, or related disciplines.

Essential Technical Skills

Strong expertise is required in Proteomics including:

• untargeted proteomics,
• DIA-based workflows,
• targeted proteomics,
• sample preparation,
• data acquisition,
• and data analysis.

Proteomics Software Experience

Knowledge of:

• Proteome Discoverer
• Spectronaut
• Skyline

is highly desirable.

Mass Spectrometry

Hands-on experience with:

• nano LC,
• high-resolution mass spectrometry,
• preferably Orbitrap instruments.

Bioinformatics and Data Science

Applicants should be comfortable working with:

• complex proteomics datasets,
• R,
• Python,
• and annotation resources such as: KEGG, Gene Ontology (GO).

Additional Preferred Skills

The following experience is considered advantageous:

• automated sample preparation,
• drug metabolism,
• pharmacokinetics (DMPK),
• and translational pharmaceutical research.

Professional Qualities

Bayer is seeking researchers who are:

• scientifically rigorous,
• creative,
• highly organized,
• collaborative,
• and capable of working in interdisciplinary research environments.

Strong presentation and communication skills are also essential.

What Bayer Offers

The company provides:

• hands-on industrial research experience,
• mentorship from experienced scientists,
• access to advanced pharmaceutical technologies,
• and professional development opportunities.

Learning and Career Development

Researchers gain access to:

• LinkedIn Learning,
• language training programs,
• interdisciplinary scientific collaboration,
• and practical pharmaceutical R&D experience.

This role is specifically designed to deepen theoretical knowledge through applied research.

Flexible Work and Employee Benefits

Bayer offers:

• flexible work arrangements,
• climate-friendly mobility support,
• corporate discounts,
• and inclusive workplace policies.

The company strongly supports:

• diversity,
• equal opportunity,
• and inclusive hiring practices.

Dynamic Shared Ownership (DSO)

Bayer highlights its Dynamic Shared Ownership (DSO) working model, which aims to:

• reduce bureaucracy,
• improve innovation,
• and empower researchers and project teams.

This reflects Bayer’s broader transformation toward more agile scientific collaboration.

Application Requirements

Applicants should submit:

• CV,
• cover letter,
• certificates,
• and academic transcripts.

The company encourages applicants to present:

• original ideas,
• interdisciplinary thinking,
• and strong research motivation.

Why This Opportunity Is Important

This postdoctoral role provides rare industrial research exposure in:

• pharmaceutical proteomics,
• translational drug development,
• and systems pharmacology.

Researchers interested in precision medicine, drug discovery, toxicology, and multi-omics pharmaceutical research will find this opportunity highly valuable for both academic and industry career pathways.

Official Application Link

Apply here: Bayer Job Application Portal

Final Thoughts

The Bayer Proteomics Postdoc position in Germany is an excellent opportunity for early-career scientists aiming to build expertise in:

• mass spectrometry,
• proteomics,
• DMPK,
• bioinformatics,
• and pharmaceutical R&D.

With access to industrial-scale research infrastructure and interdisciplinary collaboration, the role provides strong preparation for future careers in:

• biotechnology,
• pharmaceutical sciences,
• translational medicine,
• and systems biology research.